– Coughing along with the presence of blood in sputum – Sudden shortness of breath, labored breathing – If the clot is affecting the lungs which are termed as pulmonary embolism, a person may have symptoms such as: – Leg pain or tenderness which usually occurs in one leg In case the clot is in the deep veins of the legs a person may have symptoms such as: The test is used in such cases to identify the exact nature of the problem. This may include pain and swelling in the extremities, shortness of breath or headaches. The external signs and symptoms of a blood clot may vary, depending on the location of the clot. In many cases, a prolonged result obtained on a blood clotting test is also a reason for this test to be ordered. Patients might need this test when they are affected by repeated scenarios of blood clotting, abnormal bleeding or miscarriages. Why do I need to undergo a Cardiolipin IgG test? Hence it is often ordered along with a number of other tests for an accurate diagnosis. It is to be noted that this blood test for IgG antibodies does not point out any particular disease. In most cases, repeat tests are ordered after around 12 weeks and a continued presence of the antibodies at a higher percentage can indicate a more serious issue. In addition, a large percentage of the elderly population who are healthy can also have a higher percentage of these antibodies. There are a few therapeutic drugs that can also result in a higher level of these antibodies. Ailments like leukemia, alcoholic cirrhosis, and solid-organ malignancies can also result in a higher level of these antibodies. In many cases, these antibodies are also detected in patients affected by infections like hepatitis C, malaria, Lyme disease, syphilis, and HIV. In many people, a red or purple pattern under the skin of the arms and the legs, termed as livedo, may indicate a presence of these antibodies. Other risks that are involved with these antibodies include miscarriages or fetal loss, the formation of a clot on a specific heart valve termed as Libman-Sacks endocarditis, pulmonary emboli, and pulmonary hypertension. The antiphospholipid antibody syndrome can also occur in individuals who are unaffected by lupus. This is because of the fact that the risk of blood clot formations is independent of the disease activity. In many cases, the lupus anticoagulant (LA) and anticardiolipin antibody (ACL) can be detected together in the blood of a patient.įor a person affected by lupus, the presence of these antibodies can create a problem even when the disease is in control. The chance of these antibodies being at a higher level is also more for people with an autoimmune disease like lupus. Patients who have been diagnosed with an antiphospholipid antibody syndrome (APS) have an increased risk for ailments like stroke, thromboembolism, thrombocytopenia, myocardial infarction, and recurrent miscarriages. The three types of anticardiolipin antibodies are the IgG, IgA and IgM types and this particular test measures the level of IgG type antibodies in the blood. The anticardiolipin antibodies are often responsible for the abnormal formation of clots in veins and arteries which are known as phlebitis and arterial thromboses respectively. These antibodies are found in patients with various ailments including arterial and venous thrombosis, connective tissue diseases, syphilis, antiphospholipid syndrome, livedoid vasculitis, Behçet’s syndrome, systemic lupus erythematosus, and others. The phospholipids are mainly present in the cell membranes and the inner mitochondrial membranes of the body. The antiphospholipid antibodies are specific antibodies that are directed against phosphorus-fat components called phospholipids.
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